Heart Failure-USB: Prediction and Progression

Recruiting now

Conditions studied: Acute Heart Failure, Acute Coronary Syndrome, Heart Failure

In brief

This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.

Key facts

Study ID

NCT04000061

Run by

University Hospital, Basel, Switzerland

People needed

6000

Starts

2019-06-13

Expected to finish

2026-12-31

Last updated by the study team

2025-04-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients hospitalized with a primary diagnosis of ACS
• Patients hospitalized with a primary or secondary diagnosis of AHF

You may not qualify if…

• Existence of a documented statement of the patient against the scientific use of clinical data

Where it is running

• Cardiology, University Hospital Basel — Basel, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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