Etrasimod Versus Placebo as Induction Therapy in Moderately to Severely Active Ulcerative Colitis

Completed · Phase 3 · Has a placebo group

Conditions studied: Ulcerative Colitis

In brief

The purpose of this study is to assess the efficacy of etrasimod on clinical remission in participants with moderately to severely active ulcerative colitis (UC).

Key facts

Study ID

NCT03996369

Run by

Arena Pharmaceuticals

People needed

354

Starts

2020-09-15

Expected to finish

2021-12-07

Last updated by the study team

2022-12-21

Who can join

Age: 16 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with ulcerative colitis (UC) ≥ 3 months prior to screening
• Active UC confirmed by endoscopy

You may not qualify if…

• Severe extensive colitis
• Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence or history of a fistula consistent with CD
• Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis

Where it is running

• East View Medical Research, LLC — Mobile, Alabama, United States
• Arizona Digestive Health — Sun City, Arizona, United States
• Om Research, LLC — Lancaster, California, United States
• Entertainment Medical Group, Inc. — Los Angeles, California, United States
• United Medical Doctors — Murrieta, California, United States
• ACRC Studies,LLC — San Diego, California, United States
• Paradigm Clinical Research Institute — Torrance, California, United States
• University of Colorado — Aurora, Colorado, United States
• Peak Gastroenterology Associates — Colorado Springs, Colorado, United States
• Gastro Florida — Clearwater, Florida, United States
• Gastro Florida — Clearwater, Florida, United States
• Florida Center for Gastroenterology — Largo, Florida, United States
• Global Life Research Network, LLC — Miami, Florida, United States
• Life Medical Center & Research, Inc — Miami Lakes, Florida, United States
• Gastroenterology Group of Naples — Naples, Florida, United States
• NSB Research — New Smyrna Beach, Florida, United States
• Pediatric & Adult Research Center — Orlando, Florida, United States
• IMIC, Inc. — Palmetto Bay, Florida, United States
• Advanced Medical Research Center — Port Orange, Florida, United States
• Theia Clinical Research, LLC — St. Petersburg, Florida, United States
• Lenus Research & Medical Group, LLC — Sweetwater, Florida, United States
• USF Department of Surgery — Tampa, Florida, United States
• GCP Clinical Research — Tampa, Florida, United States
• Guardian Angel Research Center — Tampa, Florida, United States
• Digestive Health Specialists of the Southeast — Dothan, Alabama, United States

Full record on ClinicalTrials.gov

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