Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Stopped early · Phase 2 · Has a placebo group

Conditions studied: Cholestatic Pruritus

In brief

This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of twice-daily (BID) oral CR845 1.0 mg in patients with PBC with moderate-to-severe pruritus. The study includes a 16-week Treatment Period.

Key facts

Study ID
NCT03995212
Run by
Cara Therapeutics, Inc.
People needed
14
Starts
2019-06-25
Expected to finish
2022-06-29
Last updated by the study team
2023-07-03

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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