Bowel Function/QoL After Elective Sigmoidectomy vs. Conservative Management for Recurrent Uncomplicated Diverticulitis
Recruiting now
Conditions studied: Diverticulitis of Sigmoid
In brief
The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on low-quality evidence.The goal of this trial is to achieve a better understanding of the impact of surgery on bowel function and QoL in patients with recurrent uncomplicated sigmoid diverticulitis in order to develop treatment guidelines.
Key facts
- Study ID
- NCT03994978
- Run by
- University Hospital, Basel, Switzerland
- People needed
- 252
- Starts
- 2019-07-08
- Expected to finish
- 2028-12-31
- Last updated by the study team
- 2026-05-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with recurrent uncomplicated diverticulitis and surgical indication for sigmoid resection
- Patients with recurrent uncomplicated diverticulitis and non-surgical indication for conservative management
- Confirmation of at least one episode of acute uncomplicated diverticulitis in computed tomography
You may not qualify if…
- Patients aged under 18.
- Patients unable to understand an informed consent.
- Patients with chronic pain disorder.
- Patients with sigmoid fistulas
- Emergency operations.
- Pregnant women or lactation.
- Patients with other severe gastrointestinal diseases, such as inflammatory bowel diseases (IBD), carcinoma or immunologic disorders.
- Patients unable to perform surgery or high-risk patients according to the American Society of Anesthesiology (ASA 4 grade or higher)
Where it is running
- St. Claraspital Basel — Basel, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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