SHame prOpensity in bOrderline Personality Disorder

Recruiting now · Not applicable

Conditions studied: Borderline Personality Disorder

In brief

Borderline Personality Disorder (BPD) is a common psychiatric disorder occurring in 2 to 6% of the population. 70% of patients with BPD do at least one Suicide Attempt (SA) in their lives. It makes BPD the most related to SA condition. Negative interpersonal events are among the main stressor inducing a SA. Patients with BPD are characterized by emotional dysregulation, impulsivity (repeated parasuicidal and suicidal behaviors), and instability in interpersonal relationships. The feeling of shame related to this psychiatric disorder could be one of the causes of the high SA rate. In this study, patients with BPD will be follow-up during 5 years. The main objective is to study the propensity to feel shame as a predictor of SA. This include: * Study of shame propensity as a predictive factor of suicidal behavior - Identify homogeneous subgroups of patients with BPD based on SA, and overall functioning. * Identify biological markers predicting SA * Identify predictive and protective treatments (pharmacological and psychotherapeutic) for SA

Key facts

Study ID

NCT03994510

Run by

University Hospital, Montpellier

People needed

688

Starts

2020-09-18

Expected to finish

2031-09-01

Last updated by the study team

2025-09-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• To be over 18
• Clinical diagnosis of BPD using the SCID II (Structured Clinical Interview for DSM-IV-Text Reviewed Axis II Personality Disorders)
• Having signed the informed consent
• Able to understand the nature, the purpose and the methodology of the study
• Able to understand and perform the clinical evaluations

You may not qualify if…

• Deprived of liberty (by judicial or administrative decision)
• Protected by law (guardianship)
• Exclusion period in relation to another protocol
• Not affiliated to a social security scheme

Where it is running

• University Hospital of Montpellier — Montpellier, Hérault, France (enrolling)

Full record on ClinicalTrials.gov

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