Muscle Capillarization and Sarcopenia

Completed · Not applicable

Conditions studied: Sarcopenia

In brief

Aging is associated with a loss of muscle mass, termed sarcopenia, that reduces mobility, decreases physical function and accelerates progression of other age-related disorders. This study is designed to determine whether increasing skeletal muscle capillarization through aerobic exercise will enhance muscular adaptations to strength training in older adults with sarcopenia.

Key facts

Study ID

NCT03984994

Run by

Baltimore VA Medical Center

People needed

14

Starts

2021-11-01

Expected to finish

2024-04-30

Last updated by the study team

2025-10-29

Who can join

Age: 65 and older, up to 88. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body Mass Index = 18-32.5 kg/m2
• Non-smoker
• Presence of at least moderate sarcopenia (low muscle mass per unit body height)

You may not qualify if…

• Diagnosis of diabetes, cancer, pulmonary or renal disease
• Physical impairment preventing exercise
• Recent history of exercise training

Where it is running

• University of Maryland, Baltimore & Baltimore VA Medical Center — Baltimore, Maryland, United States
• University of Maryland — College Park, Maryland, United States

Full record on ClinicalTrials.gov

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