Neural Control of Kidney Blood Flow During Exercise in African American Adults

Recruiting now · Not applicable

Conditions studied: Healthy

In brief

The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During two visits in the research lab, participants will: * Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

Key facts

Study ID

NCT03981640

Run by

University of Massachusetts, Boston

People needed

32

Starts

2024-09-30

Expected to finish

2026-08-01

Last updated by the study team

2026-06-26

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Self-report as either African American or White racial identity
• Born in United States
• Both biological parents identify as same racial identity as participant
• Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
• Fluent in English

You may not qualify if…

• Hispanic or Latino
• Females who are pregnant or lactating
• Cardiovascular or renal disease
• Hypertension (blood pressure of more than or equal to 130/80 mmHg)
• Diabetes
• Obesity (body mass index of more than or equal to 30 kg/m2)
• Smoker/Tobacco user
• Acute medical conditions
• Taking prescribed cardiovascular, antihypertensive, or renal medications

Where it is running

• University of Massachusetts Boston — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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