Anti-oxidant Therapy and Postoperative Cardiac Events (ACE) Trial, Preoperative Intervention in Vascular Surgery

Status unconfirmed · Early Phase 1 · Has a placebo group

Conditions studied: Myocardial Injury

In brief

N Terminal (NT)-Pro b-type natriuretic peptide (BNP) levels provide incremental value in perioperative risk assessment prior to major non-cardiac surgery. The investigators will test whether pharmacologically lowering this biomarker with daily administration of CoQ10 for 3 days prior to elective vascular surgery will reduce adverse outcomes following the operation.

Key facts

Study ID

NCT03956017

Run by

Minneapolis Veterans Affairs Medical Center

People needed

341

Starts

2013-08-05

Expected to finish

2022-08-04

Last updated by the study team

2021-08-31

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• ELECTIVE HIGH RISK NON-CARDIAC SURGERY

You may not qualify if…

• REACTION TO COQ10

Where it is running

• Va Medical Center — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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