Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Completed · Phase 1

Conditions studied: Hemodialysis, Healthy

In brief

The objectives of this study are to evaluate the in vivo metabolite profiling and characterization of CR845 administered intravenously (IV) in patients on hemodialysis (HD) and in healthy subjects; and to determine the pharmacokinetics of radiolabeled \[14C\] CR845 administered as a single IV bolus in patients on HD and in healthy subjects.

Key facts

Study ID
NCT03947970
Run by
Cara Therapeutics, Inc.
People needed
12
Starts
2019-01-17
Expected to finish
2019-04-06
Last updated by the study team
2019-07-24

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.