Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Completed · Phase 3 · Has a placebo group

Conditions studied: Ulcerative Colitis

In brief

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately to severely active ulcerative colitis.

Key facts

Study ID

NCT03945188

Run by

Arena Pharmaceuticals

People needed

433

Starts

2019-06-13

Expected to finish

2022-02-16

Last updated by the study team

2022-12-20

Who can join

Age: 16 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with ulcerative colitis (UC) ≥ 3 months prior to screening
• Active UC confirmed by endoscopy

You may not qualify if…

• Severe extensive colitis
• Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence or history of a fistula consistent with CD
• Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis

Where it is running

• Arizona Digestive Health — Sun City, Arizona, United States
• Om Research, LLC — Lancaster, California, United States
• Entertainment Medical Group, Inc. — Los Angeles, California, United States
• United Medical Doctors — Murrieta, California, United States
• San Diego Gastroenterology Medical Associates — San Diego, California, United States
• ACRC Studies, LLC — San Diego, California, United States
• Peak Gastroenterology Associates — Colorado Springs, Colorado, United States
• Gastro Florida — Clearwater, Florida, United States
• West Central Gastroenterology d/b/a Gastro Florida — Clearwater, Florida, United States
• Florida Center for Gastroenterology — Clearwater, Florida, United States
• Javier Sobrado, MD — Miami, Florida, United States
• Life Medical Center & Research, INC — Miami Lakes, Florida, United States
• Gastroenterology Group of Naples — Naples, Florida, United States
• Office of Dr Meckstroth — Naples, Florida, United States
• NSB Research — New Smyrna Beach, Florida, United States
• Sarkis Clinical Trials - Parent — Ocala, Florida, United States
• IMIC, Inc. — Palmetto Bay, Florida, United States
• Advanced Medical Research Center — Port Orange, Florida, United States
• Theia Clinical Research, LLC — St. Petersburg, Florida, United States
• Advanced Research Institute, Inc. — St. Petersburg, Florida, United States
• Lenus Research & Medical Group — Sweetwater, Florida, United States
• USF Physicians Group — Tampa, Florida, United States
• GCP Clinical Research — Tampa, Florida, United States
• Guardian Angel Research Center — Tampa, Florida, United States
• Digestive Health Specialists of the Southeast — Dothan, Alabama, United States

Full record on ClinicalTrials.gov

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