Changes in the Bladder Micro-environment Following Midurethral Sling Surgery for Stress Urinary Incontinence

Status unconfirmed

Conditions studied: Stress Urinary Incontinence

In brief

This observational cohort study is aimed at determining changes in the cytokine expression profile as well as the urinary and vaginal microbiome of women undergoing midurethral sling placement for the treatment of stress urinary incontinence.

Key facts

Study ID

NCT03942549

Run by

Oregon Health and Science University

People needed

20

Starts

2019-05-03

Expected to finish

2020-12-31

Last updated by the study team

2020-09-16

Who can join

Age: 18 and older, up to 89. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age > 18 years old
• Planning to undergo retropubic midurethral sling placement

You may not qualify if…

• Prior surgery for stress urinary incontinence
• Untreated pelvic organ prolapse > Stage II based on POP-Q assessment
• Concomitant surgery for prolapse
• Current use of anticholinergic medications
• Use of systemic or vaginal antibiotics in the last 2 months
• Active urinary tract infection
• History of recurrent UTI
• Pregnancy
• History of pelvic radiation or bladder cancer

Where it is running

• Legacy Good Samaritan Hospital — Portland, Oregon, United States
• Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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