Cardiac and Renal Biomarkers in Arthroplasty Surgery

Stopped early · Phase 4

Conditions studied: Renal Injury, Anesthesia, Myocardial Injury, Arthropathy of Knee, Arthropathy of Hip

In brief

The investigators will compare the effect of spinal anesthesia to general anesthesia on the level of high sensitivity cardiac biomarkers in patients undergoing hip or knee arthroplasty. The investigators will also measure renal biomarkers in urine to evaluate kidney injury in the postoperative period.

Key facts

Study ID

NCT03940651

Run by

Washington University School of Medicine

People needed

1

Starts

2019-09-04

Expected to finish

2020-09-23

Last updated by the study team

2021-02-05

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients, age 60 years or older
• Ability to provide informed consent
• American Society of Anesthesiologists (ASA) classification II or higher

You may not qualify if…

• Hip fracture procedures
• Contraindications to neuraxial anesthesia per The American Society of Regional Anesthesia (ASRA) guidelines
• Procedure anticipated duration is longer than expected planned spinal anesthesia duration

Where it is running

• Washington University — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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