UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder
Stopped early · Phase 2
Conditions studied: Urea Cycle Disorder
In brief
UNLOCKED: A Phase 2 Trial to Evaluate the Efficacy and Safety of KB195 in Subjects with a Urea Cycle Disorder with Inadequate Control on Standard of Care
Key facts
- Study ID
- NCT03933410
- Run by
- Kaleido Biosciences
- People needed
- 13
- Starts
- 2019-09-17
- Expected to finish
- 2021-03-02
- Last updated by the study team
- 2022-01-25
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- University of South Florida/ USF HEALTH — Tampa, Florida, United States
- Johns Hopkins University School of Medicine — Baltimore, Maryland, United States
- Washington University School of Medicine — St Louis, Missouri, United States
- Icahn School of Medicine at Mount Sinai-Clinical Research Unit — New York, New York, United States
- UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States
- Cliniques Universitaires Saint-Luc — Brussels, Belgium
- Universitair Ziekenhuis Gent — Ghent, Belgium
- Zentrum für Kinder- und Jugendmedizin Angelika-Lautenschläger-Klinik — Heidelberg, Germany
- Hospital de Cruces — Barakaldo, Spain
- Hosptial Universitari Vall d'Hebron — Barcelona, Spain
- Hospital Universitario Reina Sofia — Córdoba, Spain
- Hospital Universitario Virgen del Rocio — Seville, Spain
- Inselpital, Universitaetsklinik fur Kinderheikunde — Bern, Switzerland
- Inselpital, Universitätsklinik für Kinderheilkunde — Bern, Switzerland
- Department of Child Health and Diseases, Department of Nutrition and Metabolism Istanbul University — Istanbul, Turkey (Türkiye)
- Salford Royal Hospital — Salford, Greater Manchester, United Kingdom
- National Hospital for Neurology and Neurosurgery — London, United Kingdom
- Salford Royal NHS Foundation Trust — Salford, United Kingdom
Full record on ClinicalTrials.gov
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