Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
Completed · Not applicable
Conditions studied: Post Traumatic Stress Disorder
In brief
The purpose of this research is 1) to investigate the role of the sympathetic nervous system and cardiac-vascular function in women with PTSD; and 2) to determine whether lifestyle modifications (exercise training and healthy eating) would be effective in reducing sympathetic activity, improving cardiovascular function, and improving psychiatric and quality of life outcomes in women with PTSD. It is hypothesized that (1) women with PTSD will have over-activation of the sympathetic nervous system and impaired cardiac-vascular function compared with women who are trauma free, and (2) lifestyle modifications can reduce sympathetic activity, improve cardiac-vascular function, and improve psychiatric symptoms and quality of life in women with PTSD.
Key facts
- Study ID
- NCT03929939
- Run by
- North Texas Veterans Healthcare System
- People needed
- 24
- Starts
- 2017-03-27
- Expected to finish
- 2018-01-09
- Last updated by the study team
- 2022-09-30
Who can join
Age: 18 and older, up to 65. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Be either a female veteran with a current diagnosis of PTSD (for the PTSD group) or a female non-veteran without a current diagnosis of PTSD (for the non-PTSD control group).
- Be between the ages of 18-65.
- Sedentary (exercises less than three times a week for thirty minutes or less).
You may not qualify if…
- Any evidence of cardiopulmonary and neurological diseases by history or by physical examination.
- Chronic kidney disease (serum creatinine > 1.5 mg/dL).
- Peripheral vascular disease.
- Peripheral neuropathy.
- Current substance use disorder other than tobacco related.
- Endurance-trained athletes due to the effects of exercise training on sympathetic neural control and cardiac-vascular function.
- Current pregnancy.
Where it is running
- Dallas VA Medical Center — Dallas, Texas, United States
- The Institute for Exercise and Environmental Medicine — Dallas, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.