Abobotulinumtoxina Efficacy in Post-Traumatic Headache

Completed · Phase 4 · Has a placebo group

Conditions studied: Post-Traumatic Headache

In brief

This study will evaluate the efficacy of abobotulinumtoxina on Veterans with post-traumatic headache

Key facts

Study ID

NCT03928496

Run by

VA Greater Los Angeles Healthcare System

People needed

40

Starts

2013-08-01

Expected to finish

2017-02-02

Last updated by the study team

2019-04-26

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• male or female
• age 18-65
• meets International Classification Headache Disorders II (ICHD-II) criteria for post-traumatic headache
• average pain score of greater than 4/10 in severity on the numerical rating system
• Rancho Los Amigos cognitive scale score greater than seven.

You may not qualify if…

• Uncontrolled medical condition other than PTH
• Severe additional chronic pain complaint which could not be distinguished from headache pain
• pregnancy, breast feeding,
• prior treatment with botulinum toxin within one year of enrollment
• current substance abuse/dependence
• medical condition that would increase risk of neuromuscular junction blockade with botulinum toxin (myasthenia gravis, Eaton Lambert, amyotrophic lateral sclerosis)
• poorly controlled psychiatric
• initiation of a new anti-depressant or anti-seizure medication within three months of enrolling in study
• ongoing disability or litigation claim.

Where it is running

• VA Greater Los Angeles Healthcare System — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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