Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
Stopped early
Conditions studied: Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
In brief
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of obstructive sleep apnea (OSA), baseline ventilatory status, as well as pharyngeal collapsibility of patients who are recovering from anesthesia and treated for pain with opioids. The investigators hypothesize that patients with OSA, chronic (baseline) hypoventilation and increased pharyngeal collapsibility, will be more vulnerable to opioid-induced ventilatory depression.
Key facts
- Study ID
- NCT03925610
- Run by
- Stanford University
- People needed
- 8
- Starts
- 2019-04-10
- Expected to finish
- 2020-03-30
- Last updated by the study team
- 2021-03-22
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Body mass index (BMI) equal or greater than 35 kg/m2.
- American Society of Anesthesiologists (ASA) physical status I - III patients.
- Scheduled to undergo laparoscopic roux-en-Y gastric bypass or gastric sleeve placement surgery for weight loss.
You may not qualify if…
- Chronic obstructive pulmonary disorder (COPD).
- Treatment with continuous positive airway pressure (CPAP) in the past three months.
- Severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder.
- Chronic pain condition that was being treated with opioids.
- Patients with a hematocrit lower than 35%.
Where it is running
- Stanford University School of Medicine — Stanford, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.