Short-term Clinical Deterioration After Acute Pulmonary Embolism
Completed
Conditions studied: Pulmonary Embolism
In brief
This is a prospective, observational, multicenter cohort study to compare right ventricular dysfunction dependent and independent prognostic models for short-term serous adverse events in patients who are diagnosed with pulmonary embolism in the emergency department. Clinical endpoints are assessed at days 1-5. A thirty-day follow-up phone call is conducted to obtain further clinical endpoints and a quality of life assessment.
Key facts
- Study ID
- NCT03915925
- Run by
- Wake Forest University Health Sciences
- People needed
- 935
- Starts
- 2018-09-30
- Expected to finish
- 2020-11-30
- Last updated by the study team
- 2022-04-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Men and women, 18 years or older, with image confirmed acute pulmonary embolism diagnosed within 12 hours of ED presentation
You may not qualify if…
- Patients who decline any participation in the study
- Patients 17 years old and younger at the time of screening
- Radiologist's over read that determines that filling defects identified as acute emboli are instead either chronic, resolving, or unchanged after comparison to previous CT, if available
- If empiric anticoagulation or escalated intervention were initiated more than 12 hours before presentation to the recruiting ED
- Identification of either segmental or subsegmental intraluminal filling defects on CT that are considered to be clinically incidental and unrelated to primary diagnostic workup or ED presentation.
Where it is running
- San Diego Medical Center — San Diego, California, United States
- Christiana Care Health System — Newark, Delaware, United States
- Orlando Regional Medical Center — Orlando, Florida, United States
- Carolinas Medical Center - Main — Charlotte, North Carolina, United States
- Vanderbilt Medical Center — Nashville, Tennessee, United States
- Univeristy of Utah Hospital — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
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