Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation

Recruiting now · Phase 3

Conditions studied: Tobacco Dependence

In brief

Smoking remains the single most preventable cause of morbidity and mortality in the United States, accounting for approximately half a million deaths every year. The current study will investigate the efficacy and mechanisms of change of a novel smoking cessation intervention. The current study will thus provide essential information regarding a treatment that has the potential to enhance the efficacy of existing smoking cessation interventions, thereby having a beneficial impact on the public health of the United States.

Key facts

Study ID

NCT03912194

Run by

University of Alabama at Birmingham

People needed

400

Starts

2019-08-01

Expected to finish

2026-07-01

Last updated by the study team

2026-03-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• at least 18 years of age
• smoke at least 5 cigarettes per day
• Expired breath carbon monoxide (CO) reading of at least five parts per million
• report the intention to quit
• reside in the Birmingham area with no plan to relocate outside of the area in the next 6 months
• access to a telephone

You may not qualify if…

• inability to speak English
• presence of a condition that contraindicates use of the nicotine patch
• presence of conditions that might interfere with compliance with the protocol or greatly complicate treatment
• any acutely life-threatening disease
• concurrent participation in a formal treatment program for smoking cessation
• current use of any pharmacotherapy for smoking cessation

Where it is running

• Ryals Public Health Building — Birmingham, Alabama, United States (enrolling)

Full record on ClinicalTrials.gov

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