Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Recruiting now · Not applicable

Conditions studied: Recurrent Implantation Failure

In brief

Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent Implantation Failure (RIF)

Key facts

Study ID

NCT03900780

Run by

Universitaire Ziekenhuizen KU Leuven

People needed

100

Starts

2019-05-01

Expected to finish

2026-12-31

Last updated by the study team

2025-02-26

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women with recurrent implantation failure (previous transfer of least 4 good quality embryos in at least 3 fresh or frozen cycles)
• BMI < 35
• Normal hysteroscopy

You may not qualify if…

• thin endometrium in previous cycles (<6mm), endometriosis ASRM score III-IV, premature ovarian failure (POF, Bologna criteria), abnormal karyotype, donor oocytes or embryos, PGT-M

Where it is running

• UZ Leuven — Leuven, Belgium (enrolling)

Full record on ClinicalTrials.gov

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