GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

Stopped early

Conditions studied: Dry Age-related Macular Degeneration, Macular Degeneration, Retinal Disease, Retinal Degeneration, Geographic Atrophy, Macular Atrophy

In brief

An observational study to evaluate the natural progression of dry AMD in genetically defined subjects

Key facts

Study ID

NCT03894020

Run by

Gyroscope Therapeutics Limited

People needed

83

Starts

2019-01-08

Expected to finish

2024-03-25

Last updated by the study team

2024-10-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults with unilateral or bilateral Geographic Atrophy (GA) due to Age-related Macular Degeneration (AMD)
• BCVA of 40 letters or better using ETDRS charts

You may not qualify if…

• Evidence or history of neovascular Age-related Macular Degeneration (AMD) or diabetic retinopathy
• Significant ocular or non-ocular disease that would impact the subject's ability to participate in the study
• Participation in another research study involving an investigational product within the previous 4 weeks or 5 half-lives whichever is longer from the screening/baseline OR received a gene/cell therapy at any time previously

Where it is running

• Retina Centers PC — Tucson, Arizona, United States
• Retina Vitreous Associates Medical Group — Beverly Hills, California, United States
• Byers Eye Institute at Stanford — Palo Alto, California, United States
• Retina Health Center — Fort Myers, Florida, United States
• Retina Vitreous Associates of Florida — St. Petersburg, Florida, United States
• Southeast Retina Center — Augusta, Georgia, United States
• Georgia Retina PC — Marietta, Georgia, United States
• University Retina Macula Associates PC — Lemont, Illinois, United States
• Midwest Eye Institute Northside — Indianapolis, Indiana, United States
• Wolfe Eye Clinic — West Des Moines, Iowa, United States
• The Retina Care Center — Baltimore, Maryland, United States
• Johns Hopkins University School of Medicine — Baltimore, Maryland, United States
• Ophthalamic Consultants of Boston (OCB) — Boston, Massachusetts, United States
• Pepose Vision Institute — Chesterfield, Missouri, United States
• Sierra Eye Associates — Reno, Nevada, United States
• New Jersey Retina Research Foundation — Vauxhall, New Jersey, United States
• Long Island Vitreoretinal Consultants — Great Neck, New York, United States
• Columbia University Medical Center — New York, New York, United States
• Retina Association of Western New York — Rochester, New York, United States
• Wake Forest Baptist Medical Center - Wake Forest University School of Medicine — Winston-Salem, North Carolina, United States
• Cincinnati Eye Institute — Cincinnati, Ohio, United States
• Casey Eye Institute - OHSU — Portland, Oregon, United States
• Mid-Atlantic Retina — Philadelphia, Pennsylvania, United States
• Retina Consultants of Houston-TMC — Bellaire, Texas, United States
• Retinal Research Institute (retina consultants of AZ) — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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