G.R.I.T. - Goal-directed Resilience Intervention Training

Completed · Not applicable

Conditions studied: Chronic Post-Traumatic Stress Disorder

In brief

This research program has addressed three reactive adaptations evident in pain, PTSD, and obesity. In this project, the focus will be on PTSD as a model of stimulus-based reactive responses to unpredictability or threat, and the investigators propose to test the efficacy of the goal-directed skills training (GRIT) program for restoring predictive responding and homeostasis. The challenge of how best to cultivate psychological resilience in the face of stress, trauma, and social adversity among disadvantaged populations is a complex question best answered with a translational research approach. This research' intent is to help African American women who are dealing with stress after traumatic experiences. It will specifically study Post-traumatic Stress Disorder, a disorder that affects people who have experienced severe traumas. It is associated with a number of overwhelming emotional symptoms. These include sleep difficulties, depression and anxiety, flashbacks and nightmares of the traumatic events. The training is an 8-week skill building program that helps people use positive experiences from their past to cope with current difficulties. The investigators will collect blood samples for future research to understand how the body's stress response changes as a result of this training

Key facts

Study ID

NCT03890029

Run by

Morehouse School of Medicine

People needed

38

Starts

2021-07-13

Expected to finish

2023-03-07

Last updated by the study team

2023-03-16

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• African American/Black (self-identified)
• Diagnosis of PTSD
• Between the ages of 18-64 other illnesses due to aging, cognitive declines due to aging, retirement change in life demands at age 65.
• Able and willing to provide consent

You may not qualify if…

• Active suicidality
• Active alcohol and substance use of moderate or severe levels of severity
• Psychosis
• Current severe disabling illness (recent surgery, impending surgery, extreme pain interfering with participation)
• Unable to meet attendance requirements: limit of 2 missed session of the 8.
• Not engaged in other therapies for PTSD, cognitive behavior therapy, exposure therapy and reprocessing therapy.
• Unable to participate in small group interactive setting.

Where it is running

• Grady Health Systems — Atlanta, Georgia, United States
• Morehouse School of Medicine — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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