Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma
Completed · Phase 1
Conditions studied: Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma
In brief
This study is researching an experimental drug called cemiplimab. The study is focused on Cutaneous Squamous Cell Carcinoma (CSCC) and Basal Cell Carcinoma (BCC). The aim of the study is to evaluate the safety and tolerability (how your body reacts to the drug) of cemiplimab (also known as REGN2810). The first part of the study tested several different doses of cemiplimab given weekly for 12 weeks. The study is also looking at several other research questions, including: * What side effects may happen from taking the study drug * To see effect of cemiplimab on the tumor * How much study drug is in the blood at different times
Key facts
- Study ID
- NCT03889912
- Run by
- Regeneron Pharmaceuticals
- People needed
- 97
- Starts
- 2019-04-11
- Expected to finish
- 2025-12-10
- Last updated by the study team
- 2026-01-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Medical Dermatology Specialists — Phoenix, Arizona, United States
- TCR Medical Corporation — San Diego, California, United States
- Dermatology Associates of the Palm Beaches — Delray Beach, Florida, United States
- MetroDerm — Atlanta, Georgia, United States
- Northeast Dermatology Associates — Beverly, Massachusetts, United States
- Rochester Dermatologic Surgery, P.C. — Victor, New York, United States
- Duke Cancer Center — Durham, North Carolina, United States
- The University of Texas MD Anderson Cancer Center — Houston, Texas, United States
- Inova Schar Cancer Institute — Fairfax, Virginia, United States
- Princess Alexandra Hospital — Brisbane, Queensland, Australia
- Peter MacCallum Cancer Centre — Melbourne, Victoria, Australia
- Alfred Health — Melbourne, Victoria, Australia
- Fremantle Dermatology — Fremantle, Western Australia, Australia
- Radboud University Medical Center — Nijmegen, Gelderland, Netherlands
- Maastricht University Medical Center — Maastricht, Limburg, Netherlands
- The Netherlands Cancer Institute - Antoni van Leeuwenhoek — Amsterdam, North Holland, Netherlands
- University of Groningen, University Medical Centre Groningen — Groningen, Netherlands
- Erasmus MC — Rotterdam, Netherlands
Full record on ClinicalTrials.gov
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