A Systematic Oral Care Program in Post-Mechanically Ventilated, Post-Intensive Care Patients

Completed · Not applicable

Conditions studied: Methicillin-resistant Staphylococcus Aureus, Methicillin-Sensitive Staphylococcus Aureus Infection

In brief

The purpose of this study is to see if a 4 day oral care program in patients who have been on a breathing machine results in better oral health, reduces the amount of certain bacteria in the mouth and reduces infection while in the hospital. The plan is to test the specific hypotheses that a standardized oral care protocol: 1. Results in improved oral health compared to standard care, 2. Reduces the rate of Staphylococcus aureus / methicillin resistant Staphylococcus aureus, and 3. Reduces the risk of healthcare-associated infections.

Key facts

Study ID

NCT03886623

Run by

Ohio State University

People needed

80

Starts

2011-06-01

Expected to finish

2013-12-01

Last updated by the study team

2019-03-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• Has required mechanical ventilation for at least 48 hours
• Meets ventilator liberation criteria (PEEP ≤ 8 and FiO2 ≤ 50%)
• Minimum of 3 teeth
• Either the subject or their Legally Authorized Representative is capable of reading, understanding and providing written informed consent.

You may not qualify if…

• Non-English speaking
• Allergy to products/components of the oral care protocol
• Oral or maxillofacial surgery, or oral/facial trauma in last three months
• INR > 3.5 or platelet count < 20,000
• Planned hospital discharge within 48 hours
• Current diagnosis of mucositis, or undergoing chemotherapy or radiation therapy
• Presence of Tracheostomy
• Family or physician not in favor of continued medical treatment.
• Unable to give informed consent, and/or lack of availability of an authorized representative who can provide consent

Where it is running

• The Ohio State University — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.