HVNI Ambulation Feasibility Study

Completed · Not applicable

Conditions studied: Respiratory Insufficiency, Dyspnea

In brief

The pilot/feasibility study evaluates the ability of High Velocity Nasal Insufflation (HVNI) therapy to facilitate ambulation and mobilization in patients experiencing shortness of breath, as compared to simple oxygen therapy.

Key facts

Study ID

NCT03885726

Run by

Vapotherm, Inc.

People needed

32

Starts

2018-11-21

Expected to finish

2019-03-11

Last updated by the study team

2020-10-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults over the age of 18 years
• Demonstrated respiratory distress upon mild to moderate exertion (e.g. dyspnea upon standing, walking, etc.)
• Candidate for clinical ambulation/mobilization

You may not qualify if…

• Hypoxemia at resting baseline: unable to maintain SpO2≥88% with supplemental oxygen
• Inability to provide informed consent
• Pregnancy
• Known contraindication to perform ambulation, per site SOC practices
• Inadequate respiratory drive or any known contraindications to HVNI
• Inability to use nasal cannula and HVNI therapy
• Agitation or uncooperativeness
• Determined by the attending clinician to be sufficiently unstable or unsuitable for this feasibility study

Where it is running

• Midwest Chest Consultants — Saint Charles, Missouri, United States
• Knox Community Hospital — Mount Vernon, Ohio, United States
• Riverside Regional Medical Center — Newport News, Virginia, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.