Functional Roles of Dorsolateral Prefrontal Cortex
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Healthy Participants
In brief
Dorsolateral prefrontal cortex (DLPFC) has been found to be involved in cognitive functions such as executive function, response selection, and working memory. By applying transcranial magnetic stimulation (TMS) or transcranial focused ultrasound (FUS), which is a technology to temporally alter brain state in the stimulation site, the investigators aim to find supporting evidence for the causal relationship between the targeted stimulation site and motor learning improvement or response selection.
Key facts
- Study ID
- NCT03882931
- Run by
- University of Virginia
- People needed
- 90
- Starts
- 2019-01-28
- Expected to finish
- 2020-01-27
- Last updated by the study team
- 2019-11-19
Who can join
Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy, adult subjects
- 18 to 35 years of age
- Right-handed
- Have no any type of metal in the body
- Provide written informed consent
You may not qualify if…
- Presence of a significant medical, psychiatric, or neurologic illness
- History of loss of consciousness of more than ten minutes in the past year or loss of consciousness in a lifetime that required rehabilitation services
- Personal or family history of seizure
- Any history of stroke/transient ischemic attack (TIA) or severe traumatic brain injury
- Taking any medications that may decrease the threshold for seizure
- Pregnancy (self-reported)
- Affirmative answers to one or more questions of the provided attached safety questionnaires. These are not absolute contraindications to this study but the risk/benefit ratio will be carefully balanced by the PI
- Failure to follow laboratory or study procedures
Where it is running
- University of Virginia — Charlottesville, Virginia, United States (enrolling)
Full record on ClinicalTrials.gov
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