RiSE to Prevent Cardiovascular Disease in African Americans
Completed · Not applicable
Conditions studied: Atherosclerosis, Stress, Hypertension, Dyslipidemias, Obesity, Diabetes, Coronary Artery Disease
In brief
The purpose of this pilot study is to evaluate an innovative 8-wk stress reduction program called Resilience, Stress and Ethnicity (RiSE) program designed to reduce chronic stress associated with perceived discrimination among African Americans. African Americans residing in the Maywood community between the ages of 25 and 75 with at least one cardiovascular disease risk factor such as being overweight, having high blood pressure, or diabetes will be enrolled. The following specific aims will be addressed: Aim 1: Determine the feasibility and acceptability of the program as a strategy to reduce chronic stress in African Americans within the Maywood and surrounding community. Aim 2: Examine the extent to which training in RiSE (1) improves psychological well being, (2) decreases inflammatory burden, and (3) reduces cardiovascular risk in African Americans Participants will be randomized to either the RiSE program or the control (no intervention group). Participants will provide blood and saliva samples as well as complete written questionnaires asking them questions about their health, well-being, and early life at the start of the study, half way through the study (at 4 weeks), at the completion of the intervention (8 weeks) and 3 months after the completion of the intervention).
Key facts
- Study ID
- NCT03878290
- Run by
- Loyola University
- People needed
- 74
- Starts
- 2017-08-03
- Expected to finish
- 2019-10-01
- Last updated by the study team
- 2019-10-23
Who can join
Age: 25 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- African American
- Living in Maywood community or surrounding area
- Able to speak, read, write English
- Have at least one of the following:
- Body Mass Index (BMI) > 25 (overweight or obese)
- Total cholesterol > 240
- Diabetes mellitus
- Systolic blood pressure the same or greater than 120 mmHg or diagnosis of hypertension and/or taking antihypertensive medication
- Atrial fibrillation
- Parental history of myocardial infarction (MI) (heart attack) prior to age 60
You may not qualify if…
- Current smoker (smoked in last month)
- History of myocardial infarction or ischemic heart disease
- Current cancer
- Active infection
- Major Immune-related disorder (lupus,MS)
- Substance abuse
- Immune-altering drugs
- Recent dental procedure (within past 72 hours
- Bleeding gums or periodontal disease
Where it is running
- Loyola University Chicago — Maywood, Illinois, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.