Intraoperative Assessment of of Burst Wave Lithotripsy (BWL)

Recruiting now · Not applicable

Conditions studied: Renal Calculi, Ureteral Calculi

In brief

Burst Wave Lithotripsy (BWL) is a novel method of urinary stone fragmentation that uses multi-cycle bursts of low amplitude ultrasound to induce stone fracture. This is in contrast to traditional extracorporeal shock wave lithotripsy (SWL), which employs a brief single compression/tensile cycle of high amplitude (shock) waves to achieve stone fracture. This is a single-arm feasibility study to test the ability of BWL to comminute (fragment) stones in humans.

Key facts

Study ID

NCT03873259

Run by

University of Washington

People needed

40

Starts

2019-08-08

Expected to finish

2028-04-30

Last updated by the study team

2026-07-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals presenting with at least one kidney stone apparent on CT
• Individuals scheduled for clinical stone removal via ureteroscopy (URS)

You may not qualify if…

• Individuals under 18 years of age
• Individuals belonging to a vulnerable group (pregnant, mentally disabled, prisoner, etc.)
• Individuals with uncorrected bleeding disorders or coagulopathies
• Individuals taking a clinically significant anticoagulant dose at the time of the procedure
• Individuals with a calcified abdominal aortic aneurysm or calcified renal artery aneurysm
• Individuals with a solitary kidney
• Individuals with a comorbidity risks which, at the discretion of the physician, would make the patient a poor candidate for the BWL procedure

Where it is running

• IU Health North Hospital — Carmel, Indiana, United States (enrolling)
• University of Washington Medical Center — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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