Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types
Recruiting now
Conditions studied: Diagnosis of Cancer of Various Organs
In brief
ClearNote Health is developing a test from whole blood for the early detection of multiple cancers. The goal of this study is to employ genomics, epigenomics and proteomics methodology for the detection of cancer signal in the blood of subjects with solid tumors.
Key facts
- Study ID
- NCT03869814
- Run by
- ClearNote Health
- People needed
- 20000
- Starts
- 2018-04-05
- Expected to finish
- 2029-09-13
- Last updated by the study team
- 2026-05-15
Who can join
Age: 21 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Subjects must be between 21-80 years of age at the time of enrollment
- Patient fully consented
- Cancer diagnosis OR high clinical suspicion for cancer, based on the participating site's and practitioner's standards of care (SOC)
- No previous history of cancer and treatment naïve at time of enrollment
You may not qualify if…
- Age < 21 OR > 80 years of age
- Any prior cancer diagnosis with or without treatment (with the exception of non-melanoma skin cancers resolved/treated > 1 year prior to enrollment)
- Receipt of any cancer therapy including chemotherapy, radiation, palliative radiation, hormonal or naturopathic therapies
- In situ carcinoma without an invasive component
- Any surgery requiring general anesthesia within 2 months of collection. Anesthesia used in procedures such as colonoscopy and EBUS is acceptable.
- Receipt of systemic immunomodulation therapy within past 12 months
- Currently pregnant, or pregnancy within last 12 months
- Organ transplantation
- Received dialysis
- Blood transfusion within 1 month
- Known HIV/AIDs, Hepatitis A, D, or E, TB, any kind of prion disorder (e.g., CJD) or other infectious pathogens currently present or present in past 5 years.
Where it is running
- ClearNote Health, Inc. — San Diego, California, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.