Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy

Completed · Not applicable

Conditions studied: Malignant Neoplasm, Malignant Respiratory Tract Neoplasm, Malignant Thoracic Neoplasm

In brief

This trial studies how well rapid on site evaluation of pleural touch preparations works in diagnosing cancerous fluid in between the linings of the lungs (malignant pleural effusion) in patients undergoing a pleuroscopy. A type of laboratory testing called rapid on site evaluation of pleural touch preparations that uses pleural biopsy tissue samples collected during an already-scheduled pleuroscopy may be able to diagnose malignant pleural effusion.

Key facts

Study ID

NCT03868579

Run by

M.D. Anderson Cancer Center

People needed

97

Starts

2018-01-10

Expected to finish

2025-02-27

Last updated by the study team

2025-03-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who will undergo pleuroscopy with biopsy

You may not qualify if…

• Patients with known malignant pleural effusion
• Inability or unwillingness to give informed consent

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States
• Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
• M D Anderson Cancer Center — Houston, Texas, United States
• Nicosia General Hospital — Nicosia, Cyprus

Full record on ClinicalTrials.gov

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