Exparel and Education to Avoid Opioids After Carpal Tunnel Release

Recruiting now · Phase 4

Conditions studied: Carpal Tunnel Syndrome

In brief

This trial seeks to use the long acting local anesthetic Exparel, in conjunction with opioid education, to attempt to avoid any post-operative opioid use following carpal tunnel surgery. This group will be compared with a "standard" group that receives non-liposomal bupivacaine, opioid education, and opioids.

Key facts

Study ID

NCT03867539

Run by

Kettering Health Network

People needed

64

Starts

2019-02-15

Expected to finish

2027-12-31

Last updated by the study team

2026-04-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• carpal tunnel syndrome diagnosed either by physical exam or EMG
• age >18.

You may not qualify if…

• allergy to bupivacaine
• pre-operative opioid usage within the last six months
• patients allergic to Percocet or acetaminophen
• patients taking tricyclic antidepressants (interaction with bupivacaine)
• vulnerable populations (prisoners or pregnant women)

Where it is running

• Orthopedic Associates of Southwest Ohio — Dayton, Ohio, United States (enrolling)
• Orthopedic Associates of Southwest Ohio — Dayton, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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