Capsaicin Energy Expenditure and Glucose Metabolism
Status unconfirmed · Not applicable
Conditions studied: Obesity, Insulin Resistance
In brief
The aim of the study is to investigate the effects of capsaicin rich foods on resting energy expenditure and substrate oxidation. We plan to recruit 30 healthy lean and overweight individuals age 18-45 (women) and age 18-50 (men) who will undergo two test days in random order. During one day they will receive a breakfast of toast, orange juice and an omelette with 4tsp of cayenne pepper while on the other day they will receive the same breakfast without the cayenne pepper. Metabolic rate and Respiratory quotients is measured for 30 minutes before the meal and for 2 hours after the meal. Capillary glucose levels and heart rate and blood pressure are measured before the meal and every 30 minutes thereafter for 2 hours.
Key facts
- Study ID
- NCT03859583
- Run by
- George Mason University
- People needed
- 30
- Starts
- 2018-05-29
- Expected to finish
- 2019-08-01
- Last updated by the study team
- 2019-03-01
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18-45 years of age females or 18-50 males
- Generally healthy non-diabetic overweight or obese men and women
- BMI 23-33 kg/m2
- Willing to abstain from caffeine and alcohol for 3 days prior to testing
- Able to provide written consent in English
- Ability to communicate in English (oral and written)
You may not qualify if…
- BMI < 23 kg/m2 or >33 kg/m2
- Pregnant or Nursing
- Taking prescribed or over the counter medication affecting fluid balance or metabolism
- Suffers from hepatic, renal, pulmonary, endocrine or hematological disease
- Performs more than 3 hours a week of strenuous exercise
- Consumes, on average, more than 2 alcoholic beverages per day
- More than 5 kg of weight change over the past 6 months
- Claustrophobic
- Consumes capsaicin foods habitually 3x/week
Where it is running
- George Mason University — Fairfax, Virginia, United States (enrolling)
Full record on ClinicalTrials.gov
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