CLOUD-R HAE REGISTRY

Recruiting now

Conditions studied: ANGIOEDEMA

In brief

Angioedema is a disease characterized by the appearance of self-limiting edema that last 1-5 days and affect the subcutaneous tissue and/or gastrointestinal and oropharyngeal mucosa. In this last location edema can be lethal causing asphyxia, in all other cases full recovery is complete. Attacks can appear as part of the syndrome urticaria angioedema and can be of allergic origin. But there is a group of non-allergic angioedema that occur without hives and can be either hereditary or acquired. These angioedema are identified in some cases on the basis of etiology, in others are identified by the mediator and an overall classification of these forms of angioedema was published in 2014 as a result of a consent conference organized by the proponents of this registry. Being these forms of angioedema rare, there are not significative case studies inclusive of a high number of patients. This registry aims to collect in a single place a high number of subjects with recurring angioedema and without urticaria.

Key facts

Study ID

NCT03845946

Run by

University Hospital, Grenoble

People needed

1000

Starts

2018-09-01

Expected to finish

2028-09-01

Last updated by the study team

2021-11-01

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any patient with isolated angioedema without associated wheals.
• Patients with hereditary angioedema with or without C1 deficiency.
• Major patient with consent (signature)
• Minor patient whose parents / legal guardians have given their consent (signature)

You may not qualify if…

• Patient unable to give consent.
• Wheals with angioedema

Where it is running

• University Hospital Grenoble — Grenoble, Isere, France (enrolling)

Full record on ClinicalTrials.gov

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