Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

Recruiting now · Not applicable

Conditions studied: Alcohol Use Disorder, Alcoholic Hepatitis

In brief

Given the severe consequences of alcohol relapse following liver transplantation for alcoholic hepatitis (AH-LT), it is critical to accurately identify alcohol use and implement alcohol interventions early in the post-transplant period to optimize patient outcomes. The proposed randomized clinical trial will examine the implementation and effects of integrated, person- and computer-delivered alcohol treatment compared to standard care on alcohol use (assessed by self-report and biomarker), mood, quality of life and survival following AH-LT. Predictors of 12-month post-transplant alcohol outcomes will be explored to allow future improved tailoring and targeting of these treatments.

Key facts

Study ID

NCT03845205

Run by

Johns Hopkins University

People needed

200

Starts

2020-11-20

Expected to finish

2027-06-01

Last updated by the study team

2026-06-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English speaking

You may not qualify if…

• too medically/psychiatrically ill to participate
• not able to provide informed consent due to cognitive impairment

Where it is running

• Johns Hopkins University School of Medicine — Baltimore, Maryland, United States (enrolling)

Full record on ClinicalTrials.gov

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