Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA)
Completed · Phase 3
Conditions studied: Juvenile Idiopathic Arthritis
In brief
This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form. To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (≥5 joints), uveitis, or treatment with other systemic medication within 18 months of randomization in children with recent-onset limited JIA.
Key facts
- Study ID
- NCT03841357
- Run by
- Duke University
- People needed
- 121
- Starts
- 2019-10-29
- Expected to finish
- 2025-01-22
- Last updated by the study team
- 2026-01-23
Who can join
Age: 2 and older, up to 16. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California at San Francisco Medical Center — San Francisco, California, United States
- The Children's Hospital Colorado — Aurora, Colorado, United States
- Shands at the University of Florida — Gainesville, Florida, United States
- Riley Hospital for Children at Indiana University Health — Indianapolis, Indiana, United States
- University of Iowa Hospitals of Clinics — Iowa City, Iowa, United States
- University of Louisville School of Medicine/ Norton Charities Pediatric Clinical Research Unit — Louisville, Kentucky, United States
- Boston Children's Hospital — Boston, Massachusetts, United States
- University of Minnesota; Children's Hospital and Clinics of Minnesota — Minneapolis, Minnesota, United States
- Mayo Clinic — Rochester, Minnesota, United States
- Hackensack University Medical Center — Hackensack, New Jersey, United States
- Children's Hospital at Montefiore/ Albert Einstein University Hospital — The Bronx, New York, United States
- University of North Carolina — Chapel Hill, North Carolina, United States
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
- MetroHealth System — Cleveland, Ohio, United States
- Nationwide Children's Hospital — Columbus, Ohio, United States
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
- Monroe Carell Jr Children's Hospital at Vanderbilt — Nashville, Tennessee, United States
- University of Utah — Salt Lake City, Utah, United States
- Seattle Children's Hospital — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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