A Pragmatic Trial To Determine the Benefit of Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee

Completed · Not applicable

Conditions studied: Osteoarthritis of the Knee

In brief

Knee osteoarthritis (KOA) is one of the most common and disabling conditions among Veterans. Management of KOA is challenging as there are few effective treatments other than joint replacement. Importantly, low levels of physical activity in patients with knee problems might worsen pain and disability. This study aims to determine the feasibility of using methods to change behavior that use social incentives and promote physical activity through playing games and interacting with a web-based platform. The study will also evaluate an important and widely used treatment, namely corticosteroid injections. Participants will be randomized into one of 4 arms and will receive a different combination of social incentives and injections. The study will evaluate which approach is most effective at promoting physical activity and reducing pain and disability.

Key facts

Study ID

NCT03835910

Run by

VA Office of Research and Development

People needed

34

Starts

2019-07-08

Expected to finish

2021-06-30

Last updated by the study team

2021-07-27

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Veterans in VA Rheumatology or Orthopedic clinics
• Chronic knee osteoarthritis
• Indication for joint injection
• Previous joint injections for palliation
• Patient expresses interest in increasing their physical activity
• Patient is able to walk 1/2 mile per day

You may not qualify if…

• Intra-articular hardware or other contraindication to joint injection
• Lack of smart phone
• Acute exacerbation of osteoarthritis or knee pain
• Unable or unwilling to identify a social sponsor
• Comorbid condition that precludes safe exercise

Where it is running

• Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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