Independent Weight Loss Maintenance for Communities With Arthritis in North Carolina: the I-CAN Clinical Trial
Completed · Not applicable
Conditions studied: Osteo Arthritis Knee
In brief
The study team is currently conducting a pragmatic, community-based assessor-blinded randomized controlled trial (RCT) in overweight and obese adults \> 50 years with knee OA in both urban and rural counties in North Carolina. As the participants randomized to the 18 month diet and exercise group in the WE-CAN study successfully complete the intervention (≥ 5% weight loss), the study team has the unique opportunity to evaluate the effectiveness of a theoretically-based tapered weight maintenance intervention. Eligible participants will be randomized to either the weight-loss maintenance or health education attention control groups.
Key facts
- Study ID
- NCT03832296
- Run by
- Wake Forest University Health Sciences
- People needed
- 105
- Starts
- 2018-03-29
- Expected to finish
- 2020-06-30
- Last updated by the study team
- 2021-02-26
Who can join
Age: 51 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- age ≥ 51
- achieved a weight loss ≥ 5% in the D+E intervention arm of the WE-CAN trial
You may not qualify if…
- Weight loss < 5% of baseline body weight
- Significant co-morbid disease that would threaten safety or impair ability to participate in interventions or testing (Blindness; Type 1 diabetes; Severe coronary artery disease)
- Inability to finish 18-month study or unlikely to be compliant (Planning to leave area > 2 month during the next 18 months)
Where it is running
- Johnston County - UNC Chapel Hill — Chapel Hill, North Carolina, United States
- Haywood County - Haywood Regional Medical Center — Clyde, North Carolina, United States
- Forsyth County - Wake Forest University/Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
Full record on ClinicalTrials.gov
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