Transcranial Direct Current Stimulation for Post-stroke Motor Recovery
Completed · Phase 2 · Has a placebo group
Conditions studied: Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
In brief
This research study is to find out if brain stimulation at different dosage level combined with an efficacy-proven rehabilitation therapy can improve arm function. The stimulation technique is called transcranial direct current stimulation (tDCS). The treatment uses direct currents to stimulate specific parts of the brain affected by stroke. The adjunctive rehabilitation therapy is called "modified Constraint-Induced Movement Therapy" (mCIMT). During this therapy the subject will wear a mitt on the hand of the arm that was not affected by a stroke and force to use the weak arm. The study will test 3 different doses of brain stimulation in combination with mCIMT to find out the most promising one.
Key facts
- Study ID
- NCT03826030
- Run by
- Duke University
- People needed
- 129
- Starts
- 2019-09-01
- Expected to finish
- 2024-09-19
- Last updated by the study team
- 2025-08-22
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Alabama at Birmingham Hospital — Birmingham, Alabama, United States
- Keck Hospital of USC — Los Angeles, California, United States
- MedStar National Rehabilitation Hospital — Washington D.C., District of Columbia, United States
- Emory Rehabilitation Hospital — Atlanta, Georgia, United States
- Cardinal Hill Rehabilitation Hospital — Lexington, Kentucky, United States
- Baystate Medical Center — Springfield, Massachusetts, United States
- Burke Rehabilitation Center — White Plains, New York, United States
- Duke University Hospital — Durham, North Carolina, United States
- University of Cincinnati Medical Center — Cincinnati, Ohio, United States
- Cleveland VA Medical Center — Cleveland, Ohio, United States
- Moss Rehabilitation Research Institute — Elkins Park, Pennsylvania, United States
- University of Pittsburgh Medical Center Presbyterian Hospital — Pittsburgh, Pennsylvania, United States
- Medical University of South Carolina University Hospital — Charleston, South Carolina, United States
- Memorial Hermann Texas Medical Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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