Pilocarpine and Brimonidine in Patients With Monofocal Lenses
Status unconfirmed · Early Phase 1
Conditions studied: Presbyopia, Pseudophakia
In brief
The current study aims to assess the use of pilocarpine and brimonidine to improve near visual acuity in patietns with monofocal intraocular lenses. Thirty-three subjects with be enrolled and baseline visual acuity with be measured at near and distance. This will be compared to visual acuity after drop administration over 6 hours. A quality of life questionnaire will also be evaluated.
Key facts
- Study ID
- NCT03825081
- Run by
- Massachusetts Eye and Ear Infirmary
- People needed
- 33
- Starts
- 2019-01-21
- Expected to finish
- 2019-12-31
- Last updated by the study team
- 2019-01-31
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Individuals must meet all of the inclusion criteria in order to be eligible to participate in the study. Men and women between ages 60 years and above with monofocal intraocular lenses bilaterally corrected for distance and +/- 0.5D sphere vision who need only +/- 2.5 D correction for reading. Given the age group selected only post menopausal women will be evaluated.
You may not qualify if…
- Individuals meeting any of the exclusion criteria at baseline will be excluded from study participation including: allergies to proparacaine, pilocarpine or brimonidine, eye infection or inflammation, glaucoma, retinal tear or retinal disease, eye surgery within the past 30 days, use of eye drops within the last seven days, participated in any other research study within the past 30 days. Patients using contact lenses.
Where it is running
- Massachusetts Eye and Ear — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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