The Influence of Personal Care Products on the Skin Microbiome

Completed · Not applicable

Conditions studied: Microbiome

In brief

To evaluate whether personal care products shift the skin microbiome bacteria and diversity after a week of daily use.

Key facts

Study ID

NCT03819179

Run by

University of California, Davis

People needed

30

Starts

2017-12-01

Expected to finish

2018-02-06

Last updated by the study team

2019-01-28

Who can join

Age: 20 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Females, aged 20-45 (limiting to females so that there is not heterogeneity with the influence of hormones. Also, females are a much larger user base of personal care products)
• Individuals in good general health
• Individuals free of any dermatological or systemic disorder, which would interfere with the results, at the discretion of the investigator
• Individuals who have participated in any other clinical studies using the same test sites (face) in the past 14 days

You may not qualify if…

• Individuals who have been on any topical antibiotic for the past one month or oral antibiotic therapy for the past 2 months or are currently on any antibiotic therapy
• Individuals who have history of acute or chronic disease that would likely interfere with or increase the risk on study participation at the discretion of the investigator
• Individuals with active (flaring) disease or chronic skin allergies (atopic dermatitis/eczema) or those who have recently undergone treatment for skin cancer (within the last 12 months) in the area of testing on the nose and the cheeks
• Female volunteers who are pregnant or are actively nursing
• Female volunteers who have started a new hormonal birth control agent or switched to a hormonal birth control agent within the past 60 days
• Individuals who have had any medical or cosmetic procedure, such as laser resurfacing, or plastic surgery to the test site (face) within the last 6 months. This includes botulinum toxin, dermal fillers, collagen or other similar cosmetic procedure
• Individuals who are currently using or during the past 30 days have used a retinoid such as Retin A, or other Rx/over the counter (OTC) Retinyl A or currently using or during the past 14 days have used hydroquinone (skin lightening)
• Individuals with a known history of hypersensitivity to any ingredients to the cosmetic agent that is being assessed
• Individuals with self-reported oily skin that may predispose them to acne form breakouts (at the discretion of the investigator)

Where it is running

• UC Davis Department of Dermatology, Clinical Trials Unit — Sacramento, California, United States

Full record on ClinicalTrials.gov

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