Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis

Completed · Phase 2 · Has a placebo group

Conditions studied: Prurigo Nodularis, Pruritis

In brief

Study of the efficacy, safety, tolerability, pharmacokinetics (PK), and immunogenicity of Vixarelimab (KPL-716) in subjects with prurigo nodularis (PN).

Key facts

Study ID

NCT03816891

Run by

Genentech, Inc.

People needed

240

Starts

2019-03-11

Expected to finish

2023-08-24

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Investigate MD, LLC — Scottsdale, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• First OC Dermatology — Fountain Valley, California, United States
• Center for Dermatology Clinical Research, Inc. — Fremont, California, United States
• Dermatology Research Associates — Los Angeles, California, United States
• Wallace Medical Group, Inc. — Los Angeles, California, United States
• Velocity Clinical Research - North Hollywood — North Hollywood, California, United States
• Colorado Center for Dermatology, PLLC — Centennial, Colorado, United States
• George Washington University Medical Faculty Associates — Washington D.C., District of Columbia, United States
• Rybear, Inc. — Fort Lauderdale, Florida, United States
• University of Florida, Department of Dermatology — Gainesville, Florida, United States
• Olympian Clinical Research — Largo, Florida, United States
• University of Miami Itch Center — Miami, Florida, United States
• Riverchase Dermatology — Pembroke Pines, Florida, United States
• Olympian Clinical Research — St. Petersburg, Florida, United States
• Advanced Clinical Research Institute — Tampa, Florida, United States
• Palm Harbor Dermatology — Tampa, Florida, United States
• Olympian Clinical Research — Tampa, Florida, United States
• Alliance Clinical Research of Tampa — Tampa, Florida, United States
• Integrated Clinical Research — West Palm Beach, Florida, United States
• Advanced Medical Research PC — Sandy Springs, Georgia, United States
• DS Research — New Albany, Indiana, United States
• DS Research — Louisville, Kentucky, United States
• ALLCUTIS Research, LLC — Beverly, Massachusetts, United States
• Arizona Research Center — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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