Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia
Completed · Phase 3
Conditions studied: Hypertension, FXTAS
In brief
To study whether heart rate variability training and respiratory coherence can improve hypertension in individuals with FXTAS. All patients will receive HRV biofeedback training for 20 sessions. Our hypothesis is that individuals with FXTAS who undergo 20 sessions of biofeedback training will improve self-regulatory skills for reducing hypertension, as measured by blood pressure measurement to below 140/90. The investigators hypothesize that individuals who successfully develop increased heart rate variability and better synchrony between heart rhythm and respiration will show the greatest improvements in self-regulatory skills for hypertension.
Key facts
- Study ID
- NCT03816540
- Run by
- University of California, Davis
- People needed
- 20
- Starts
- 2018-05-01
- Expected to finish
- 2019-03-13
- Last updated by the study team
- 2019-10-22
Who can join
Age: 50 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Males and females between the ages of 50-90 with a molecular documentation of a fragile X premutation, diagnosed with FXTAS.
- stable current pharmacological treatment regimen for at least 4 weeks.
- English speaking (the intervention is currently only available in English)
- Clinically significant hypertension.
- Normal or corrected to normal vision and hearing.
You may not qualify if…
- Significant medical and behavioral problems that would interfere with the study (e.g. not being able to sit and play a computer game for 10 minutes)
- Participants who plan to initiate or change pharmacologic or non-pharmacologic interventions during the course of the study
- Individual is non-verbal (has no spoken language)
- English is not the primary language.
- Clinically critical Hypertension that requires medical attention
Where it is running
- University of California, Davis, MIND Institute — Sacramento, California, United States
Full record on ClinicalTrials.gov
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