Below Knee DVT Study

Stopped early · Phase 4

Conditions studied: Deep Vein Thrombosis (DVT), Blood Clots

In brief

Hospitalized patients are at risk of developing blood clots in the legs (Deep Vein Thrombosis or DVT), which can lead to death if those clots break off and migrate to the lungs. We know that if there is a blood clot in the large leg veins near the hips and in the thighs, treating these patients with high-doses of blood thinners reduces the risk of these deaths. It is unclear if treating blood clots in the calf with high doses of blood thinners is better than using low doses. In this study, after being diagnosed with a blood clot in the calf, patients will be treated with either low dose or high dose enoxaparin (Lovenox), a blood thinner. We will then see if low dose blood thinner has similar results as high dose blood thinner.

Key facts

Study ID

NCT03805672

Run by

Oregon Health and Science University

People needed

4

Starts

2014-09-01

Expected to finish

2015-07-01

Last updated by the study team

2019-03-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients over the age of 18 admitted to a trauma or general surgery service will be eligible
• Patients diagnosed with an isolated distal DVT
• Able to obtain informed consent

You may not qualify if…

• Patients with a previous diagnosis of hypercoagulability
• Patients on chronic anticoagulation
• Patients with a history of heparin induced thrombocytopenia
• Patients have preexisting contraindications to anticoagulation
• Patients in renal failure requiring adjusted enoxaparin dosing
• Pregnant patients

Where it is running

• Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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