Fecal Microbiota Transplantation for Ulcerative Colitis

Recruiting now · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Ulcerative Colitis, Fecal Microbiota Transplantation

In brief

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. Fecal microbiota transplantation has been used for several disease，but the efficacy of ulcerative colitis(UC) by fecal microbiota transplantation needs to be further explored.The investigators propose to determine the efficiency and safety of FMT in patients with ulcerative colitis(UC).

Key facts

Study ID

NCT03804931

Run by

Guangzhou First People's Hospital

People needed

120

Starts

2019-01-20

Expected to finish

2030-12-31

Last updated by the study team

2019-01-15

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Active, moderate to severe severity (Mayo score more than 6)
• Safety using history of 5-ASA
• Able to undergo endoscopy examination

You may not qualify if…

• Antibiotic using in 7 days
• High risk of toxic megacolon
• Colon cancer or neoplasia in pathophysiology
• Other severe diseases (eg: cardiovascular, respiratory, gastroenteral and kidney diseases)

Where it is running

• Guangzhou First People's Hospital — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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