Skeletal Muscle Function in Interstitial Lung Disease

Recruiting now · Not applicable

Conditions studied: Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis, Scleroderma, Nonspecific Interstitial Pneumonia

In brief

Dyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why. It has been suggested that muscle dysfunction may contribute to dyspnea and exercise intolerance in ILD. Our study aims to: i) examine differences in the structure and function of the leg muscles in ILD patients, ii) determine if leg muscle fatigue contributes to dyspnea and exercise limitation in patients with ILD, and iii) determine the effects of breathing extra oxygen on leg muscle fatigue, as well as ability to exercise in ILD patients.

Key facts

Study ID
NCT03800017
Run by
University of British Columbia
People needed
40
Starts
2024-08-07
Expected to finish
2026-12-31
Last updated by the study team
2026-05-15

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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