Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome

Completed · Not applicable

Conditions studied: Acute Respiratory Distress Syndrome, ARDS

In brief

Doctors follow a standard ventilator management strategy when making adjustments to the breathing machine to optimize the amount of oxygen into the lungs. The purpose of this study is to assess whether the EIT (electrical impedance tomography) device can be an additional useful tool for ventilator management and identifying the ideal positive end-expiratory pressure (PEEP).

Key facts

Study ID

NCT03793842

Run by

University of Michigan

People needed

16

Starts

2019-03-04

Expected to finish

2022-06-24

Last updated by the study team

2023-10-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Endotracheal ventilation for < 1 week (168 hours)
• Presence of all of the following conditions for < 48 hours i. Partial pressure of oxygen to percentage of inspired oxygen (PaO2/FiO2) < 150 with PEEP > 5 cm water for > 30 min.
• ii. bilateral opacities not fully explained by effusions, lobar/lung collapse, or nodules iii. respiratory failure not fully explained by cardiac failure or fluid overload
• All criteria listed in (3) developed within 1 week of a known clinical insult or new or worsening respiratory symptoms

You may not qualify if…

• Lack of informed consent
• Known pregnancy
• Extracorporeal membrane oxygenation (ECMO) use
• Severe chronic respiratory disease requiring home oxygen therapy or ventilation
• Calculated BMI of greater than 50

Where it is running

• The University of Michigan — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.