Virtual Reality- Working Memory Retraining

Completed · Not applicable

Conditions studied: Alcohol Use Disorder, Mild Traumatic Brain Injury

In brief

This study will establish the acceptability and feasibility of enrolling and retaining heavy drinking Veterans with mild traumatic brain injury (mTBI) in an 8-week, randomized cross-over design trial of active VR working memory retraining (WMR). This study will also seek to establish the efficacy of active VR-WMR to increase performance in executive function.

Key facts

Study ID

NCT03786276

Run by

University of California, San Francisco

People needed

30

Starts

2019-02-01

Expected to finish

2020-03-31

Last updated by the study team

2020-05-04

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• must report "heavy" drinking by NIH/NIAAA criteria (>7 drinks/week for women; >14 drinks/week for men) for at least one week in the last 90 days
• must meet moderate to severe criteria for current (past year) alcohol use disorder (AUD) by DSM-5
• must express a desire to reduce, stop, or maintain cessation of alcohol use
• must report a history of TBI as defined by American Congress of Rehabilitation Medicine (ACRM), in the chronic, stable phase of recovery (>6 months from injury)

You may not qualify if…

• Unstable medical or psychiatric disorders judged to be unstable in the clinical judgment of the PI
• Current or past history of intrinsic cerebral tumors, HIV infection, cerebrovascular accident, aneurysm, arteriovenous malformations, myocardial infarction, cerebrovascular or peripheral vascular disease, type-1 diabetes, any cardiac, hepatic or renal diseases/disorders, surgical implantation of neurostimulators or cardiac pacemakers, medically diagnosed chronic obstructive pulmonary disease, demyelinating and neurodegenerative diseases, history of seizure disorder, and/or any physical disability making it impossible to use exercise equipment
• No female participant will be pregnant or attempting to conceive
• Concurrent participation in an AUD, cognitive training, or exercise study
• Must not require acute medical detoxification from alcohol (CIWA-AD > 11) within the past week prior to study entry
• Subjects who, in the opinion of the investigator, are otherwise unsuitable for a study of this type will be excluded

Where it is running

• VA Medical Center San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.