Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube
Running, not enrolling · Early Phase 1
Conditions studied: Fallopian Tube Cancer, Fallopian Tube Infection
In brief
This study will evaluate the impact of low dose aspirin on normal fallopian tube fimbriae in women who have surgery to have their fallopian tubes removed. Participants will take a low dose of aspirin for 2 weeks before their surgery. A portion of the removed fallopian tubes will also be collected for future research and routine pathology purposes.
Key facts
- Study ID
- NCT03771651
- Run by
- University of Oklahoma
- People needed
- 18
- Starts
- 2019-03-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-02-17
Who can join
Age: 18 and older, up to 99. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Women undergoing gynecologic surgery for presumed benign indications that includes the removal of their fallopian tubes. This may include sterilization procedures, hysterectomy or partial or full adnexectomy.
- Eligible women will have fulfilled their childbearing desires
- Age > 21 Considered low risk for prevalent fallopian tube cancer (not undergoing risk reducing surgery for a known BRCA mutation or other known hereditary predisposition syndrome, family history of ovarian cancer in a first degree relative.
You may not qualify if…
- Males
- Women who have presumed or known gynecologic cancer
- Women less than 21 years of age
- Women currently on either regular aspirin therapy, non-steroidal anti-inflammatory drugs (NSAIDS), acetaminophen or chronic steroidal anti-inflammatory medications.
- Women with known bleeding diathesis or bleeding disorder.
- Women who do not consent for removal of both fallopian tubes.
- Women with a history of gastritis or peptic ulcer disease requiring treatment. (Patients with a history of occasional H1 or H2 blocker use for gastro esophageal reflux disease are NOT excluded).
- Women with reported aspirin or NSAID allergy
- Women with asthma and/or nasal polyps
Where it is running
- Stephenson Cancer Center, University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
Full record on ClinicalTrials.gov
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