A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy

Running, not enrolling · Phase 3

Conditions studied: Immunoglobulin A Nephropathy

In brief

To determine the long-term (approximately 2 years) nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with immunoglobulin A nephropathy (IgAN).

Key facts

Study ID

NCT03762850

Run by

Travere Therapeutics, Inc.

People needed

406

Starts

2018-12-11

Expected to finish

2026-07-01

Last updated by the study team

2026-04-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Travere Investigational Site — Homewood, Alabama, United States
• Travere Investigational Site — Glendale, California, United States
• Travere Investigational Site — Montebello, California, United States
• Travere Investigational Site — Northridge, California, United States
• Travere Investigational Site — San Diego, California, United States
• Travere Investigational Site — San Diego, California, United States
• Travere Investigational Site — Stanford, California, United States
• Travere Investigational Site — Denver, Colorado, United States
• Travere Investigational Site — Coral Springs, Florida, United States
• Travere Investigational Site — Hollywood, Florida, United States
• Travere Investigational Site — Miami, Florida, United States
• Travere Investigational Site — Miami, Florida, United States
• Travere Investigational Site — Winter Park, Florida, United States
• Travere Investigational Site — Lawrenceville, Georgia, United States
• Travere Investigational Site — Nampa, Idaho, United States
• Travere Investigational Site — Hinsdale, Illinois, United States
• Travere Investigational Site — Muncie, Indiana, United States
• Travere Investigational Site — Kansas City, Kansas, United States
• Travere Investigational Site — Louisville, Kentucky, United States
• Travere Investigational Site — Boston, Massachusetts, United States
• Travere Investigational Site — Springfield, Massachusetts, United States
• Travere Investigational Site — Worcester, Massachusetts, United States
• Travere Investigational Site — Minneapolis, Minnesota, United States
• Travere Investigational Site — Reno, Nevada, United States
• Travere Investigational Site — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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