Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion

Completed · Not applicable

Conditions studied: Calcium Oxalate Urolithiasis

In brief

The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of healthy participants and to determine whether this influences the oxalate passed in urine.

Key facts

Study ID

NCT03752684

Run by

University of Alabama at Birmingham

People needed

26

Starts

2018-04-02

Expected to finish

2025-05-22

Last updated by the study team

2026-01-30

Who can join

Age: 19 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Good health as judged from a medical history and reported medications
• Not colonized with O. formigenes

You may not qualify if…

• History of any hepatic, renal, bowel or endocrine disease or any other condition that may influence the absorption, transport or urinary excretion of ions, which will compromise the interpretation of results
• colonized with O. formigenes
• abnormal urine chemistries or blood metabolic profiles

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.