The Microbiome and Resilience to Sleep and Circadian Disruption

Completed · Not applicable · Has a placebo group

Conditions studied: Sleep Deprivation, Circadian Dysregulation, Stress

In brief

This study is about how sleep loss and being awake at night impacts the ability to think, changes molecules in the blood, and alters the bacteria that live in the gut that typically help keep people healthy. This work will have important implications for the development of treatments and countermeasures for people who do not sleep enough and need to be active at different times of the day and night (e.g., emergency workers and military personnel).

Key facts

Study ID

NCT03747367

Run by

University of Colorado, Boulder

People needed

55

Starts

2015-10-21

Expected to finish

2020-03-16

Last updated by the study team

2026-06-17

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy
• Currently residing at Denver altitude or higher

You may not qualify if…

• Current major medical disorder
• Experiment 1 and 2, ages 18-35. Experiment 3 and 4, 18-45. Experiment 3 only: Early Morning Shift Workers Experiment 4 only: Individuals Receiving Less than 6.5 hours of Sleep At Night

Where it is running

• Sleep and Chronobiology Laboratory — Boulder, Colorado, United States

Full record on ClinicalTrials.gov

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